The critical issue of the development of antimicrobial resistance in animal and human bacteria requires an integrated approach across all types of medicine, in line with the implementation of the "One Health" concept.  ANSES plays a very active role in the fight against antimicrobial resistance, in particular by coordinating the French Surveillance Network for Antimicrobial Resistance in Pathogenic Bacteria of Animal Origin (Resapath), which is devoted to monitoring antimicrobial resistance in most of the bacteria responsible for infections in all animal species. Resapath is both an essential tool for monitoring animal antimicrobial resistance and a key partner for stakeholders in human and veterinary medicine.

Veterinary antimicrobial sales have been monitored annually by the Agency since 1999. Monitoring of these sales is based on the recommendations in Chapter 6.8 of the OIE's 2016 Terrestrial Animal Health Code "Monitoring of the quantities and usage patterns of antimicrobial agents used in food-producing animals.