Antimicrobial resistance is recognised as a major problem for human and animal health worldwide. The emergence and growing spread of antibiotic-resistant bacterial strains calls into question the effectiveness of antimicrobial treatments, both in humans and in animals. Requiring the integration and interaction of a wide variety of skills and knowledge, the work conducted by ANSES is organised into five themes and involves the laboratories at Ploufragan-Plouzané, Fougères, Maisons-Alfort, Dozulé and Lyon, as well as the Risk Assessment Department and the French Agency for Veterinary Medicinal Products (ANMV).
Antimicrobial resistance is a major public health issue concerning both human and veterinary medicine. Monitoring of sales of veterinary antimicrobials is one of the main sources of information used to assess and manage the risks associated with antimicrobial resistance. Veterinary antimicrobial sales have been monitored annually by the Agency since 1999, based on the recommendations of the World Organisation for Animal Health (OIE). In addition, since 2010, ANSES has represented France in the European Surveillance of Veterinary Antimicrobial Consumption (ESVAC) project launched by the European Medicines Agency (EMA) at the request of the European Commission. Its aim is to collect harmonised data on antimicrobial sales in all countries of the European Union.
Antimicrobial resistance is a major international human and animal health issue, because the emergence and spread of drug-resistant strains of bacteria call into question the efficacy of these treatments in humans and animals alike. Preserving the effectiveness of antibiotics is therefore a genuine public health challenge requiring an integrated approach across all types of medicine, according to the "One Health" concept covering both humans and animals. ANSES has mobilised significant resources to address the topic of antibiotic resistance. Through all its research, reference, surveillance and risk assessment activities, the Agency contributes to a greater understanding of the risks associated with antimicrobial resistance related to farming, food and the environment and, therefore, ultimately the risks to human health.
Antimicrobial resistance is recognised as a major problem at international level in terms of both human and animal health, with the emergence, selection and growing spread of strains of bacteria resistant to antibiotics. The development of alternatives to antibiotics is therefore one of the measures being considered to combat this phenomenon. In this context, the Agency received a formal request to assess the benefits and risks associated with the use of zinc oxide in the diet of piglets at weaning to reduce the use of antibiotics to control digestive disorders occurring during this period. This work is presented below.
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